Valproic Acid

Valproic Acid

Product Name : Valproic Acid

Grade : IP / BP / USP

Therapeutic Category : Antiepileptic
CAS No : 99-66-1

COA : Available

MSDS : Available

Description

Valproic acid and its derivative, divalproex, are oral drugs that are used for the treatment of convulsions, migraines and bipolar disorder. The active ingredient in both products is valproic acid. Divalproex is converted to valproic acid in the stomach. The most popular theory is that valproic acid exerts its effects by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter, a chemical that nerves use to communicate with one another.

Specification

  • Identification
    • A.H-NMR: Comply with the structure (Result: Complies)
    • B.LC-MS: Comply with the structure (Result: Complies)
    • C.The IR spectrum of sample should be identical with that of reference standard (Result: Complies)
    • D.HPLC-ESI-MS: The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay (Result: Complies)
  • Crystallinity meets the requirements (Result: Complies)
  • Loss on drying ≤2.0% (Result: 0.19%)
  • Heavy metals ≤10 ppm (Result: <10ppm)
  • Water ≤1.0% (Result: 0.1%)
  • Sulphated ash ≤0.5%, determined on 1.0 g (Result: 0.009%)
  • Related substances
    • Unspecified impurities: for each impurity ≤0.10% (Result: <0.10%)
    • Total Impurity ≤0.5% (Result: 0.18%)
  • Purity ≥99.0% (Result: 99.7%)
  • Assay 99.0%~101.0% (anhydrous substance) (Result: 99.8%)
  • Microbiological Analysis
  • Total plate count ≤1000cfu/g (Result: Complies)
  • Yeast and Moulds ≤100cfu/g (Result: Complies)
  • E. Coli. Absent (Result: Negative)
  • Salmonella Absent (Result: Negative)
  • S.aureus Absent (Result: Negative)
  • Storage Preserve in well-closed, light-resistant and airtight containers (Result: Complies)

Packaging details

Packaging details: 25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.

Shelf Life: 5 years if sealed and store away from direct sun light.

Additional Information

The most widely recognized markets for this item incorporate the accompanying nations. If you don’t mind ask with us if your nation or district isn’t recorded:

ASIA: Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Afghanistan, Israel, Jordan, Pakistan, Russia, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, and so forth..

AFRICA: South Africa, Uganda, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, and so forth.

NORTH & SOUTH AMERICA: Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela, USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Brazil, Bahamas, Ecuador, and so forth .

EUROPE: France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Austria, Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, and so forth.

OCEANIA: Fiji, Australia, New Zealand, and so forth.